Enhancer-binbing protein

AIM:To explore the effects on transcription levels of CCAAT/enhancer-binding proteins (CEBP)genes and genes regulated in liver regeneration(LR).

目的:探讨基因转录水平CCAAT增强子结合蛋白(CEBPs)及其调节基因在肝再生(LR)中的作用。

BACKGROUND & OBJECTIVE: CCAAT-enhancer binding protein ε (C/EBPε) is a kind of nuclear transcriptional factor expressed predominantly in myeloid cells, and may be a critical regulator of myeloid differentiation, which can activate the transcription of a subset of myeloid-specific genes.

背景与目的:CCAAT-增强子结合蛋白(CCAAT-enhancerbindingproteinε,C/EBPε)是一种在髓系细胞中特异性表达的核内转录因子,可能是髓系细胞分化过程中重要的调控因子,并且参与了一系列髓系细胞特异性基因的转录激活。

Objective To investigate the effect of overexpression CCAAT/enhancer binding proteins ε(C/EBPε) on the phosphoinositide 3-kinase γ(PI3Kγ) gene.

目的研究过量表达转录因子CCAAT-增强子结合蛋白ε(CCAAT/enhancerbindingproteins,C/EBPε)对磷脂酰肌醇-3激酶γ(phosphoinositide3kinase,PI3Kγ)基因的影响。