extreme fiber stress

Objective To observe expression changes of stress fiber, vinculin and FAK in the formation of rat hepatic fibrosis and investigate the role of actin cytoskeleton in the formation of hepatic fibrosis.

目的　观察应力纤维 (stressfiber)、纽蛋白 (vinculin)和粘着斑激酶 (FAK)在实验性大鼠肝纤维化形成过程中的变化 ,探讨肌动蛋白在肝纤维化形成中的作用机制。

Meanwhile the coomassie brilliant blue staining method is used to detect the influence of Rabdosin B on the stress fiber which has relations with the adherence of HepG2 cells.

采用显微观察法、生长曲线法检测Rabdosin B对人肝癌细胞HepG2的增殖抑制和致死效应;同时采用考马斯亮蓝染色法检测该化合物对与细胞贴壁性相关的应力纤维的影响,以探讨对映-贝壳杉烷二萜化合物Rabdosin B对人肝癌细胞HepG2的增殖影响及致其死亡的作用。

It was found that stress fibers in ECs were induced by shear stress.

结果内皮细胞中央出现应力纤维,G_0/G_1期细胞增加。